Oral Carcinoma Cuniculatum

A Case Report

Authors

  • Jose Carnate Jr. University of the Philippines - Manila
  • Leila Salera University of the East, Manila
  • Cynthia del Castillo Saint Jude Hospital and Medical Center, Manila
  • Jay Hansel Tabije Saint Jude Hospital and Medical Center, Manila

DOI:

https://doi.org/10.21141/PJP.2019.06

Keywords:

oral squamous cell carcinoma, oral squamous cell carcinoma variant, oral carcinoma, mouth neoplasms

Abstract

We report a case a of oral carcinoma cuniculatum, an exophytic variant of oral squamous cell carcinoma that has bland cytomorphologic features, and a peculiar and characteristic growth pattern. Despite the lack of cytologic atypia, the tumor exhibited locally aggressive and infiltrative behavior with bone and cutaneous involvement. Pertinent benign and malignant mimics, and helpful differentiating features are also discussed.

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Author Biographies

Jose Carnate Jr., University of the Philippines - Manila

Professor III, Department of Pathology

Leila Salera, University of the East, Manila

Faculty, College of Dentistry

Cynthia del Castillo, Saint Jude Hospital and Medical Center, Manila

Oromaxillofacial Surgeon, Section of Oral and Maxillofacial Surgery and Implantology

Jay Hansel Tabije, Saint Jude Hospital and Medical Center, Manila

Oromaxillofacial Surgeon, Section of Oral and Maxillofacial Surgery and Implantology

References

1. Sloan P, Gale N, Hunter K, et al. Malignant surface epithelial tumours: squamous cell carcinoma. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, eds. WHO classification of tumours of the head and neck. 4th ed. Lyon: IARC Press; 2017.

2. Raja RS, Weinreb I, Bullock MJ, et al. College of American Pathologists Protocol for the examination of specimens from patients with cancers of the lip and oral cavity Version LipOralCavity 4.0.0.1; 2017. Available from: https://cap.objects.frb.io/protocols/cp-headandneck-lip-oralcavity-17protocol-4001.pdf. Accessed May 9, 2018.

3. Datar UV, Kale A, Mane D. Oral carcinoma cuniculatum: a new entity in the clinicopathological spectrum of oral squamous cell carcinoma. J Clin Diagn Res. 2017;11(1): ZD37-9. https://pubmed.ncbi.nlm.nih.gov/28274074. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324519. https://doi/org/10.7860/JCDR/2017/23437.9226.

4. Farag AF, Abou-Alnour DA, Abu-Taleb NS. Oral carcinoma cuniculatum, an unacquainted variant of oral squamous cell carcinoma: a systematic review. Imaging Sci Dent. 2018;48(4):233-44. https://pubmed.ncbi.nlm.nih.gov/30607347. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305781. https://doi.org/10.5624/isd.2018.48.4.233.

5. Zidar N, Cardesa A, Gillison M, Hekkiwekk T, Hille J, Nadal A. Verrucous carcinoma. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ eds. WHO classification of head and neck tumorus. 4th ed. Lyon: IARC Press; 2017.

6. El-Mofty SK, Cardesa A, Helliwell T, et al. Papillary squamous cell carcinoma. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, eds. WHO classification of head and neck tumours. 4th ed. Lyon: IARC Press; 2017.

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Published

05/13/2019

How to Cite

Carnate Jr., J., Salera, L., del Castillo, C., & Tabije, J. H. (2019). Oral Carcinoma Cuniculatum: A Case Report. The Philippine Journal of Pathology, 4(1), 34–36. https://doi.org/10.21141/PJP.2019.06

Issue

Vol. 4 No. 1 (2019): June Issue (Online)

Section

Case Reports

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