A Case of Dentinogenic Ghost Cell Tumor
Abstract
Among the ghost cell lesions, Dentinogenic Ghost Cell Tumors (DGCT) are among the rarest. We report a case of a 45-year-old Filipino man, who presented with a right mandibular mass. Microscopic examination showed a solid neoplasm composed of islands of odontogenic epithelium with areas showing aberrant keratinization forming ghost cells and dentinoid material. We also discuss the pertinent differential diagnosis of ghost cell-containing odontogenic tumors. We report this case due to its rarity, its morphological resemblance to ameloblastoma, and its potential for malignant transformation.
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References
Carlos R, Ledesma-Montes C. Dentinogenic ghost cell tumour. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. WHO classification of head and neck tumors, 4th ed. IARC: Lyon; 2017.
Bafna SS, Joy T, Tupkari JV, Landge JS. Dentinogenic ghost cell tumor. J Oral Maxillofac Pathol. 2016;20(1):163. PMID: 27194885. PMCID: PMC4860925. https://doi.org/10.4103/0973-029X.180985.
Bilodeau EA, Prasad JL, Alawi F, Seethala RR. Molecular and genetic aspects of odontogenic lesions. Head Neck Pathol. 2014;8(4):400–10. PMID: 25409852. PMCID: PMC4245404. https://doi.org/10.1007/s12105-014-0588-7.
Kim SA, Ahn SG, Kim SG, et al. Investigation of the β-catenin gene in a case of dentinogenic ghost cell tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;103(1):97–101. PMID: 17178501. https://doi.org/10.1016/j.tripleo.2005.10.037.
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The Philippine Journal of Pathology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Based on works made open access at http://philippinejournalofpathology.org
