Brain Metastasis of Papillary Ovarian Adenocarcinoma

Authors

  • Sonia Chhabra Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India
  • Niti Dalal Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India https://orcid.org/0000-0003-0862-0426
  • Sunita Singh Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India

DOI:

https://doi.org/10.21141/PJP.2022.05

Keywords:

brain, metastases, ovarian, adenocarcinoma

Abstract

Brain metastasis from epithelial ovarian cancer is a rare diagnostic entity with a reported incidence of 1- 2%. Serous epithelial ovarian cancer is usually associated with a poor prognosis and is the most common malignancy metastasizing to the brain. The median time from primary diagnosis to development of cerebral lesions is directly correlated with the initial tumour grade and stage.  The median survival after diagnosis of brain metastases is 6 months. It is suggested that brain imaging studies should be included in the follow up of patients after treatment for ovarian carcinoma. We report a case of brain metastasis of ovarian adenocarcinoma 2 years post-surgery and six cycles of chemotherapy.

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Author Biographies

Sonia Chhabra, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India

Professor, Department of Pathology

Niti Dalal, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India

Senior Resident, Department of Pathology

Sunita Singh, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India

Senior Professor and Head, Department of Pathology

References

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2. Thakur S, Fotedar V, Gupta M. Brain metastasis in epithelial ovarian carcinoma: case series. J Radiat Cancer Res. 2020;11(1):34-7. https://doi.org/10.4103/jrcr.jrcr_11_20.
3. Kato MK, Tanase Y, Uno M, Ishikawa M, Kato T. Brain metastases from uterine cervical and endometrial cancer. Cancers (Basel). 2021;13(3):519. https://pubmed.ncbi.nlm.nih.gov/33572880. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866278. https://doi.org/10.3390/cancers13030519.
4. Longo R, Platini C, Eid N, et al. A late, solitary brain metastasis of epithelial ovarian carcinoma. BMC Cancer. 2014;14:543. https://pubmed.ncbi.nlm.nih.gov/25069863. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122771. https://doi.org/10.1186/1471-2407-14-543.

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Published

04/22/2022

How to Cite

Chhabra, S., Dalal, N., & Singh, S. (2022). Brain Metastasis of Papillary Ovarian Adenocarcinoma. PJP, 7(1), 50–52. https://doi.org/10.21141/PJP.2022.05

Issue

Vol. 7 No. 1 (2022): June Issue (Online)

Section

Case Reports

License

Creative Commons License
The Philippine Journal of Pathology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.  Based on works made open access at http://philippinejournalofpathology.org