Dedifferentiated Chordoma in a 53-year-old Female: A Case Report

Authors

  • Criston Manasan Philippine General Hospital
  • Jose Carnate, Jr. College of Medicine, University of the Philippines Manila

Keywords:

chordoma, dedifferentiated chordoma, bone tumor, bone malignancy

Abstract

Dedifferentiated Chordomas are rare variants of a malignant bone tumor arising from remnants of the embryonal notochord. Most cases are reported from chordomas that have recurred after surgical resection and/or radiation. Dedifferentiated Chordomas have an overall poorer prognosis compared with conventional chordomas due to their highly aggressive behavior and high metastatic potential. We report a case of a Dedifferentiated Chordoma from the sacrum in a 53-year-old female with no known prior surgery or radiation treatment. The associated clinical and radiologic features are discussed along with a review of the reported cases in the English literature. The diagnostic pitfalls and approach for Chordomas as well as the current and developing treatment modalities are also reviewed.

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Author Biographies

Criston Manasan, Philippine General Hospital

Department of Laboratories, Medical Officer III

Jose Carnate, Jr., College of Medicine, University of the Philippines Manila

Consultant and Faculty, Department of Pathology, UP College of Medicine

References

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Published

02/06/2018

How to Cite

Manasan, C., & Carnate, Jr., J. (2018). Dedifferentiated Chordoma in a 53-year-old Female: A Case Report. PJP, 3(1), 12. Retrieved from https://philippinejournalofpathology.org/index.php/PJP/article/view/46

Issue

Vol. 3 No. 1 (2018): April Issue (Online)

Section

Case Reports

License

Creative Commons License
The Philippine Journal of Pathology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.  Based on works made open access at http://philippinejournalofpathology.org