An Insight into the Histopathology of Oral Neoplasms with Basaloid Morphology and a Working Classification
Keywords:
basal cell tumors, basaloid morphology, oral cavityAbstract
Basal cell tumors (BCT) are tumors usually derived from pluripotential stem cell compartments of the basal layer of epidermis and/or oral epithelium. BCTs are infrequent entities in the oral cavity and are not discussed separately in general and oral pathology. A literature review did not reveal any classification of tumors with basaloid morphology. This paper is an attempt to categorize the oral neoplasms with basaloid morphology and discuss their differential diagnoses in detail. A review of the literature was carried out to rule out the frequency of different oral BCTs reported in the literature. Additionally, a simple working classification of oral BCTS has been proposed. We hope that this classification will be helpful for oral and general pathologists and students.
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References
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15. DeVilliers P, Liu H, Suggs C, Simmons D, Daly B, Zhang S, et al. Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol. 2008; 32(2):256-60. PMID: 18223328. https://doi.org/10.1097/PAS.0b013e3181452176.
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18. Ide F, Shimoyama T, Horie N. Basaloid squamous cell carcinoma versus basal cell ameloblastoma. Oral Oncol. 1998; 34(2):154-5. PMID: 9682780.
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21. Patil AV, Tupsakhare SD, Shah K, Gabhane M, Ali FM. Basaloid squamous cell carcinoma of gingiva: a new case and review of literature. Am J Cancer Case Rep. 2014; 2:99-107.
22. Sundharam BS, Krishnan PA. Basaloid squamous cell carcinoma report of a case and review of literature. Indian J Dent Res. 2003;14(3):184 6. PMID: 15164662.
23. Ide F, Shimoyama T, Horie N. Kusama K. Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature. Oral Oncol. 2002; 38(1):120 4. PMID: 11755833.
24. Emanuel P, Wang B, Wu M, Burstein DE. Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. Mod Pathol. 2005; 18(5):645-50. PMID: 15529180. https://doi.org/10.1038/modpathol.3800329.
25. Begum S, Westra WH. Basaloid squamous cell carcinoma of the head and neck is a mixed variant that can be further resolved by HPV status. Am J Surg Pathol. 2008; 32(7):1044–50. PMID: 18496144. https://doi.org/10.1097/PAS.0b013e31816380ec.
26. Vasudev P, Boutross-Tadross O, Radhi J. Basaloid squamous cell carcinoma: two case reports. Cases J. 2009; 2:9351. PMID: 20062602. PMCID: PMC2804002. https://doi.org/10.1186/1757-1626-2-9351.
27. Wain SL, Kier R, Vollmer RT, Bossen EH. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol. 1986; 17(11):1158–66. PMID: 3770734.
28. Bajpai M, Agarwal D, Bhalla A, Kumar M, Garg R, Kumar M. Multilocular unicystic ameloblastoma of mandible. Case Rep Dent 2013; 2013:835892. PMID: 24106618. PMCID: PMC3782764. https://doi.org/ 10.1155/2013/835892.
29. Kramer IR, Pindborg JJ, Shear M. Histological typing of odontogenic tumors, 2nd ed. Berlin: Springer-Verlag, 1992.
30. Saify F, Sharma N. Basal cell ameloblastoma: a rare case report and review of literature. Oral Maxillofac Pathol J 2010; 1:1-7. http://www.ompj.org/files/b9724b4e67cc8a4760a2004b52b6550a-fatima.pdf.
31. Shakya H, Khare V, Pardhe N, Mathur E, Chouhan M. Basal cell ameloblastoma of mandible: a rare case report with review. Case Rep Dent. 2013; 2013:187820. PMID: 23653864. PMCID: PMC3638548. https://doi.org/10.1155/2013/187820.
32. Chiu NC, Wu HM, Chou YH, Li WY, Chiou YY, Guo WY, et al. Basal cell adenoma versus pleomorphic adenoma of the parotid gland. AJR Am J Roentgenol. 2007; 189(5): W254-1. PMID: 17954621. https://doi.org/10.2214/AJR.07.2292.
33. Batsakis JG, Luna MA, el-Naggar AK. Basaloid monomorphic adenomas. Ann Otol Rhinol Laryngol. 1991; 100(8):687–90. PMID: 1872522. https://doi.org/10.1177/000348949110000818.
34. Bajpai M. Canalicular adenoma arising in buccal mucosa. J Coll Physician Surg Pak. 2016; 26(11):46. PMID: 27981939.
35. Fonseca I, Soares J. Basal cell adenocarcinoma of minor salivary and seromucous glands of the head and neck region. Semin Diagn Pathol. 1996; 13(2):128-37. PMID: 8734419.
36. Hirsch DL, Miles C, Dierks E. Basal cell adenocarcinoma of the parotid gland: report of a case and review of the literature. J Oral Maxillofac Surg. 2007; 65(11):2385-8. PMID: 17954345. https://doi.org/10.1016/j.joms.2006.07.021.
37. Parashar P, Baron E, Papadimitriou JC, Ord RA, Nikitakis NG: Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007, 103(1):77-84. PMID: 17178498. https://doi.org/10.1016/j.tripleo.2005.12.021.
38. Jung MJ, Roh JL, Choi SH, Nam SY, Kim SY, Lee SW, et al. Basal cell adenocarcinoma of the salivary gland: a morphological and immunohistochemical comparison with basal cell adenoma with and without capsular invasion. Diagn Pathol. 2013; 8:171. PMID: 24143938. PMCID: PMC4016524. https://doi.org/10.1186/1746-1596-8-171.
39. Martínez-Rodríguez N, Leco-Berrocal I, Rubio-Alonso L, Arias-Irimia O, Martínez-González JM. Epidemiology and treatment of adenoid cystic carcinoma of the minor salivary glands: a meta-analytic study. Med Oral Patol Oral Cir Bucal. 2011; 16(7):e884-9. PMID: 21743416.
40. Eneroth CM, Hjertman L, Moberger G. Adenoid cystic carcinoma of the palate. Acta Otolaryngol.1968; 66(3):248–60. PMID: 4303189.
2. Nemade SV, Rokade VV. Basaloid carcinoma: an unusual presentation. Indian J Clin Pract. 2013; 23(11):728-30. http://imsear.hellis.org/handle/123456789/182519.
3. Nagao T, Sugano I, Ishida Y, Hasegawa M, Matsuzaki O, Konno A, et al. Basal cell adenocarcinoma of the salivary glands: comparison with basal cell adenoma through assessment of cell proliferation, apoptosis, and expression of p53 and bcl-2. Cancer. 1998; 82:439-47. PMID: 9452259.
4. Carr RA, Taijbee SM, Sanders DSA. Basaloid skin tumours: basal cell carcinoma. Curr Diagn Pathol. 2007; 13(4):252–72. https://doi.org/10.1016/j.cdip.2007.05.005.
5. Basarab T, Orchard G, Russell-Jones R. The use of immunostaining for bcl-2 and CD34 and the lectin peanut agglutinin in differentiating between basal cell carcinomas and trichoepitheliomas. Am J Dermatopathol 1998; 20(5):448–52. PMID: 9790103.
6. Thariat J, Badoual C, Faure C, Butori C, Marcy PY, Righini CA. Basaloid squamous cell carcinoma of the head and neck: role of HPV and implication in treatment and prognosis. J Clin Pathol. 2010; 63(10):857–66. PMID: 20876315. https://doi.org/10.1136/jcp.2010.078154.
7. Bajpai M, Pardhe N, Arora M. Intra–oral basal cell carcinomaan immunohistochemical interpretation using Ber-Ep4. J Ayub Med Coll Abbottabad. 2016; 28(2):438. PMID: 28718582.
8. Mori M, Morimoto Y, Yoshimura Y, Kawamura H. Enzymatic histochemical demonstration of basal-cell carcinoma in the oral cavity. Oral Surg Oral Med Oral Pathol. 1968; 25(5):746–55. PMID: 5239097.
9. Bath-Hextall F, Leonardi-Bee J, Smith C, Meal A, Hubbard R. Trends in incidence of skin basal cell carcinoma. Additional evidence from a UK primary care database study. Int J Cancer. 2007; 121(9):2105–8. PMID: 17640064. https://doi.org/10.1002/ijc.22952.
10. Liroff KP, Zeff S. Basal cell carcinoma of the palatal mucosa. J Oral Surg. 1972; 30(10):730-3. PMID: 4506539.
11. Bajpai M, Pardhe N. Peripheral ameloblastoma with mixed histological patterns. Cukurova Med J. 2015; 40(Suppl 1):151–5. https//doi.org/10.17826/cutf.32647.
12. Woods TR, Cohen DM, Islam MN, Kratochvil FJ, Stewart JC, Reeder SL, et al.. Intraoral basal cell carcinoma, a rare neoplasm: report of three new cases with literature review. Head Neck Pathol. 2014; 8(3):339-48. PMID: 24202723. PMCID: PMC4126916. https://doi.org/10.1007/s12105-013-0505-5.
13. Philipsen HP, Reichart PA, Nikai H, Takata T, Kudo Y. Peripheral ameloblastoma: biological profile based on 160 cases from the literature. Oral Oncol. 2001; 37(1):17-27. PMID: 11120479.
14. Del Rosario RN, Barr RJ, Jensen JL, Cantos KA. Basal cell carcinoma of the buccal mucosa. Am J Dermatopathol. 2001; 23(3):203–5. PMID: 11391100.
15. DeVilliers P, Liu H, Suggs C, Simmons D, Daly B, Zhang S, et al. Calretinin expression in the differential diagnosis of human ameloblastoma and keratocystic odontogenic tumor. Am J Surg Pathol. 2008; 32(2):256-60. PMID: 18223328. https://doi.org/10.1097/PAS.0b013e3181452176.
16. Alaeddini M, Etemad-Moghadam S, Baghaii F. Comparative expression of calretinin in selected odontogenic tumours: a possible relationship to histogenesis. Histopathology. 2008; 52(3):299-304. PMID: 18269580. https://doi.org/ 10.1111/j.1365-2559.2007.02948.x.
17. Anandani C, Metgud R, Singh K. Calretinin as a diagnostic adjunct for ameloblastoma. Pathol Res Int. 2014; 2014:308240. PMID: 24839578. PMCID: PMC4009281. https://doi.org/ 10.1155/2014/308240.
18. Ide F, Shimoyama T, Horie N. Basaloid squamous cell carcinoma versus basal cell ameloblastoma. Oral Oncol. 1998; 34(2):154-5. PMID: 9682780.
19. Greene FL, Page DL, Fleming ID, eds. AJCC/UICC cancer staging handbook: TNM clasification of malignant tumors. 7th ed. New York: Springer-Verlag, 2009.
20. Ereño C, Gaafar A, Garmendia M, Etxezarraga C, Bilbao FJ, López JI. Basaloid squamous cell carcinoma of the head and neck: a clinicopathological and follow-up study of 40 cases and review of the literature. Head Neck Pathol. 2008; 2(2):83–91. PMID: 20614328. PMCID: PMC2807543. https://doi/org/10.1007/s12105-008-0045-6.
21. Patil AV, Tupsakhare SD, Shah K, Gabhane M, Ali FM. Basaloid squamous cell carcinoma of gingiva: a new case and review of literature. Am J Cancer Case Rep. 2014; 2:99-107.
22. Sundharam BS, Krishnan PA. Basaloid squamous cell carcinoma report of a case and review of literature. Indian J Dent Res. 2003;14(3):184 6. PMID: 15164662.
23. Ide F, Shimoyama T, Horie N. Kusama K. Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature. Oral Oncol. 2002; 38(1):120 4. PMID: 11755833.
24. Emanuel P, Wang B, Wu M, Burstein DE. Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. Mod Pathol. 2005; 18(5):645-50. PMID: 15529180. https://doi.org/10.1038/modpathol.3800329.
25. Begum S, Westra WH. Basaloid squamous cell carcinoma of the head and neck is a mixed variant that can be further resolved by HPV status. Am J Surg Pathol. 2008; 32(7):1044–50. PMID: 18496144. https://doi.org/10.1097/PAS.0b013e31816380ec.
26. Vasudev P, Boutross-Tadross O, Radhi J. Basaloid squamous cell carcinoma: two case reports. Cases J. 2009; 2:9351. PMID: 20062602. PMCID: PMC2804002. https://doi.org/10.1186/1757-1626-2-9351.
27. Wain SL, Kier R, Vollmer RT, Bossen EH. Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol. 1986; 17(11):1158–66. PMID: 3770734.
28. Bajpai M, Agarwal D, Bhalla A, Kumar M, Garg R, Kumar M. Multilocular unicystic ameloblastoma of mandible. Case Rep Dent 2013; 2013:835892. PMID: 24106618. PMCID: PMC3782764. https://doi.org/ 10.1155/2013/835892.
29. Kramer IR, Pindborg JJ, Shear M. Histological typing of odontogenic tumors, 2nd ed. Berlin: Springer-Verlag, 1992.
30. Saify F, Sharma N. Basal cell ameloblastoma: a rare case report and review of literature. Oral Maxillofac Pathol J 2010; 1:1-7. http://www.ompj.org/files/b9724b4e67cc8a4760a2004b52b6550a-fatima.pdf.
31. Shakya H, Khare V, Pardhe N, Mathur E, Chouhan M. Basal cell ameloblastoma of mandible: a rare case report with review. Case Rep Dent. 2013; 2013:187820. PMID: 23653864. PMCID: PMC3638548. https://doi.org/10.1155/2013/187820.
32. Chiu NC, Wu HM, Chou YH, Li WY, Chiou YY, Guo WY, et al. Basal cell adenoma versus pleomorphic adenoma of the parotid gland. AJR Am J Roentgenol. 2007; 189(5): W254-1. PMID: 17954621. https://doi.org/10.2214/AJR.07.2292.
33. Batsakis JG, Luna MA, el-Naggar AK. Basaloid monomorphic adenomas. Ann Otol Rhinol Laryngol. 1991; 100(8):687–90. PMID: 1872522. https://doi.org/10.1177/000348949110000818.
34. Bajpai M. Canalicular adenoma arising in buccal mucosa. J Coll Physician Surg Pak. 2016; 26(11):46. PMID: 27981939.
35. Fonseca I, Soares J. Basal cell adenocarcinoma of minor salivary and seromucous glands of the head and neck region. Semin Diagn Pathol. 1996; 13(2):128-37. PMID: 8734419.
36. Hirsch DL, Miles C, Dierks E. Basal cell adenocarcinoma of the parotid gland: report of a case and review of the literature. J Oral Maxillofac Surg. 2007; 65(11):2385-8. PMID: 17954345. https://doi.org/10.1016/j.joms.2006.07.021.
37. Parashar P, Baron E, Papadimitriou JC, Ord RA, Nikitakis NG: Basal cell adenocarcinoma of the oral minor salivary glands: review of the literature and presentation of two cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007, 103(1):77-84. PMID: 17178498. https://doi.org/10.1016/j.tripleo.2005.12.021.
38. Jung MJ, Roh JL, Choi SH, Nam SY, Kim SY, Lee SW, et al. Basal cell adenocarcinoma of the salivary gland: a morphological and immunohistochemical comparison with basal cell adenoma with and without capsular invasion. Diagn Pathol. 2013; 8:171. PMID: 24143938. PMCID: PMC4016524. https://doi.org/10.1186/1746-1596-8-171.
39. Martínez-Rodríguez N, Leco-Berrocal I, Rubio-Alonso L, Arias-Irimia O, Martínez-González JM. Epidemiology and treatment of adenoid cystic carcinoma of the minor salivary glands: a meta-analytic study. Med Oral Patol Oral Cir Bucal. 2011; 16(7):e884-9. PMID: 21743416.
40. Eneroth CM, Hjertman L, Moberger G. Adenoid cystic carcinoma of the palate. Acta Otolaryngol.1968; 66(3):248–60. PMID: 4303189.
Published
09/08/2017
How to Cite
Bajpai, M., & Pardhe, N. (2017). An Insight into the Histopathology of Oral Neoplasms with Basaloid Morphology and a Working Classification. PJP, 2(2), 20. Retrieved from https://philippinejournalofpathology.org/index.php/PJP/article/view/69
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