@article{Uyboco_Cruz_Cenizal_So_Bello_Moran_2021, title={Mixed Small Cell and Large Cell Neuroendocrine Carcinoma of the Endometrium: A Case Report and Literature Review}, volume={6}, url={https://philippinejournalofpathology.org/index.php/PJP/article/view/217}, DOI={10.21141/PJP.2021.05}, abstractNote={<p>Neuroendocrine carcinoma (NEC) of the endometrium is a rare, aggressive subtype of endometrial cancer.  We report a 61-year-old female with a history of breast cancer, s/p modified radical mastectomy, chemotherapy, radiotherapy and hormonal (tamoxifen) therapy, who  presented with post-menopausal bleeding. Patient underwent TAH-BSO with lymph node dissection, and was diagnosed with a mixed small cell neuroendocrine carcinoma (SCNEC) and large cell neuroendocrine carcinoma (LCNEC), confirmed by positive immunohistochemical staining for neuroendocrine markers.  No other lesions were identified on PET-CT, making a primary endometrial NEC the most likely diagnosis.  We review the clinical and pathologic characteristics of endometrial neuroendocrine carcinomas.</p>}, number={1}, journal={PJP}, author={Uyboco, Joshua and Cruz, Mary Anne and Cenizal, Maria Concepcion and So, Jeffrey and Bello, Maximino and Moran, Jose}, year={2021}, month={Jun.}, pages={43–49} }